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Article Date(s)
Article Title
05/12/2022 - 05/23/2031
Introduction of Diindolylmethane powder (dim)
summary The activation of cytochrome P450 3A4 (CYP3A4) and multidrug resistance protein 1 (MDR1) regulated by human pregnane X receptor (hPXR) plays an important role in mediating adverse drug interactions. Given the common use of natural products as part of adjunct human health behavior, there is a growing concern about natural products for their potential to induce undesired drug interactions through the activation of hPXR-regulated CYP3A4 and MDR1. Here, we studied whether...
05/09/2022
Report of phenibut with WHO
Phenibut powder is a psychotropic drug that was developed in Russia where it is purportedly clinically used to treat a multitude of health issues,such as tension,anxiety,depression,stuttering,migraine headaches,tension headaches,alcohol withdrawal,restless leg syndrome,post-traumatic stress syndrome,insomnia,and fear,however limited information in this regard is available. Its specific indications and its off-label use are unknown. It is also purportedly used clinically in a few other Eastern...